AI for Business

Explore the best AI for Business — independent reviews, comparisons, pricing and step-by-step how-to guides, curated by Aizhi.

  • Universal portfolio algorithm

    Universal portfolio algorithm

    The universal portfolio algorithm is a portfolio selection algorithm from the field of machine learning and information theory. The algorithm learns adaptively from historical data and maximizes log-optimal growth rate in the long run, per the Kelly criterion. It was introduced by the late Stanford University information theorist Thomas M. Cover. The algorithm rebalances the portfolio at the beginning of each trading period. At the beginning of the first trading period it starts with a naive diversification. In the following trading periods the portfolio composition depends on the historical total return of all possible constant-rebalanced portfolios. The universal portfolio algorithm is the predecessor of the various online portfolio selection methodologies.

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  • Probit model

    Probit model

    In statistics, a probit model is a type of regression where the dependent variable can take only two values, for example married or not married. The word is a portmanteau, coming from probability + unit. The purpose of the model is to estimate the probability that an observation with particular characteristics will fall into a specific one of the categories; moreover, classifying observations based on their predicted probabilities is a type of binary classification model. A probit model is a popular specification for a binary response model. As such it treats the same set of problems as does logistic regression using similar techniques. When viewed in the generalized linear model framework, the probit model employs a probit link function. It is most often estimated using the maximum likelihood procedure, such an estimation being called a probit regression. == Conceptual framework == Suppose a response variable Y is binary, that is it can have only two possible outcomes which we will denote as 1 and 0. For example, Y may represent presence/absence of a certain condition, success/failure of some device, answer yes/no on a survey, etc. We also have a vector of regressors X, which are assumed to influence the outcome Y. Specifically, we assume that the model takes the form P ( Y = 1 ∣ X ) = Φ ( X T β ) , {\displaystyle P(Y=1\mid X)=\Phi (X^{\operatorname {T} }\beta ),} where P is the probability and Φ {\displaystyle \Phi } is the cumulative distribution function (CDF) of the standard normal distribution. The parameters β are typically estimated by maximum likelihood. It is possible to motivate the probit model as a latent variable model. Suppose there exists an auxiliary random variable Y ∗ = X T β + ε , {\displaystyle Y^{\ast }=X^{T}\beta +\varepsilon ,} where ε ~ N(0, 1). Then Y can be viewed as an indicator for whether this latent variable is positive: Y = { 1 Y ∗ > 0 0 otherwise } = { 1 X T β + ε > 0 0 otherwise } {\displaystyle Y=\left.{\begin{cases}1&Y^{}>0\\0&{\text{otherwise}}\end{cases}}\right\}=\left.{\begin{cases}1&X^{\operatorname {T} }\beta +\varepsilon >0\\0&{\text{otherwise}}\end{cases}}\right\}} The use of the standard normal distribution causes no loss of generality compared with the use of a normal distribution with an arbitrary mean and standard deviation, because adding a fixed amount to the mean can be compensated by subtracting the same amount from the intercept, and multiplying the standard deviation by a fixed amount can be compensated by multiplying the weights by the same amount. To see that the two models are equivalent, note that P ( Y = 1 ∣ X ) = P ( Y ∗ > 0 ) = P ( X T β + ε > 0 ) = P ( ε > − X T β ) = P ( ε < X T β ) by symmetry of the normal distribution = Φ ( X T β ) {\displaystyle {\begin{aligned}P(Y=1\mid X)&=P(Y^{\ast }>0)\\&=P(X^{\operatorname {T} }\beta +\varepsilon >0)\\&=P(\varepsilon >-X^{\operatorname {T} }\beta )\\&=P(\varepsilon 0 {\displaystyle t,\lim _{n\rightarrow \infty }n_{t}/n=c_{t}>0} . Denote p ^ t = r t / n t {\displaystyle {\hat {p}}_{t}=r_{t}/n_{t}} σ ^ t 2 = 1 n t p ^ t ( 1 − p ^ t ) φ 2 ( Φ − 1 ( p ^ t ) ) {\displaystyle {\hat {\sigma }}_{t}^{2}={\frac {1}{n_{t}}}{\frac {{\hat {p}}_{t}(1-{\hat {p}}_{t})}{\varphi ^{2}{\big (}\Phi ^{-1}({\hat {p}}_{t}){\big )}}}} Then Berkson's minimum chi-square estimator is a generalized least squares estimator in a regression of Φ − 1 ( p ^ t ) {\displaystyle \Phi ^{-1}({\hat {p}}_{t})} on x ( t ) {\displaystyle x_{(t)}} with weights σ ^ t − 2 {\displaystyle {\hat {\sigma }}_{t}^{-2}} : β ^ = ( ∑ t = 1 T σ ^ t − 2 x ( t ) x ( t ) T ) − 1 ∑ t = 1 T σ ^ t − 2 x ( t ) Φ − 1 ( p ^ t ) {\displaystyle {\hat {\beta }}={\Bigg (}\sum _{t=1}^{T}{\hat {\sigma }}_{t}^{-2}x_{(t)}x_{(t)}^{\operatorname {T} }{\Bigg )}^{-1}\sum _{t=1}^{T}{\hat {\sigma }}_{t}^{-2}x_{(t)}\Phi ^{-1}({\hat {p}}_{t})} It can be shown that this estimator is consistent (as n→∞ and T fixed), asymptotically normal and efficient. Its advantage is the presence of a closed-form formula for the estimator. However, it is only meaningful to carry out this analysis when individual observations are not available, only their aggregated counts r t {\displaystyle r_{t}} , n t {\disp

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  • Elastic net regularization

    Elastic net regularization

    In statistics and, in particular, in the fitting of linear or logistic regression models, the elastic net is a regularized regression method that linearly combines the L1 and L2 penalties of the lasso and ridge methods. Nevertheless, elastic net regularization is typically more accurate than both methods with regard to reconstruction. == Specification == The elastic net method overcomes the limitations of the LASSO (least absolute shrinkage and selection operator) method which uses a penalty function based on ‖ β ‖ 1 = ∑ j = 1 p | β j | . {\displaystyle \|\beta \|_{1}=\textstyle \sum _{j=1}^{p}|\beta _{j}|.} Use of this penalty function has several limitations. For example, in the "large p, small n" case (high-dimensional data with few examples), the LASSO selects at most n variables before it saturates. Also if there is a group of highly correlated variables, then the LASSO tends to select one variable from a group and ignore the others. To overcome these limitations, the elastic net adds a quadratic part ( ‖ β ‖ 2 {\displaystyle \|\beta \|^{2}} ) to the penalty, which when used alone is ridge regression (known also as Tikhonov regularization). The estimates from the elastic net method are defined by β ^ ≡ argmin β ( ‖ y − X β ‖ 2 + λ 2 ‖ β ‖ 2 + λ 1 ‖ β ‖ 1 ) . {\displaystyle {\hat {\beta }}\equiv {\underset {\beta }{\operatorname {argmin} }}(\|y-X\beta \|^{2}+\lambda _{2}\|\beta \|^{2}+\lambda _{1}\|\beta \|_{1}).} The quadratic penalty term makes the loss function strongly convex, and it therefore has a unique minimum. The elastic net method includes the LASSO and ridge regression: in other words, each of them is a special case where λ 1 = λ , λ 2 = 0 {\displaystyle \lambda _{1}=\lambda ,\lambda _{2}=0} or λ 1 = 0 , λ 2 = λ {\displaystyle \lambda _{1}=0,\lambda _{2}=\lambda } . Meanwhile, the naive version of elastic net method finds an estimator in a two-stage procedure : first for each fixed λ 2 {\displaystyle \lambda _{2}} it finds the ridge regression coefficients, and then does a LASSO type shrinkage. This kind of estimation incurs a double amount of shrinkage, which leads to increased bias and poor predictions. To improve the prediction performance, sometimes the coefficients of the naive version of elastic net is rescaled by multiplying the estimated coefficients by ( 1 + λ 2 ) {\displaystyle (1+\lambda _{2})} . Examples of where the elastic net method has been applied are: Support vector machine Metric learning Portfolio optimization Cancer prognosis == Reduction to support vector machine == It was proven in 2014 that the elastic net can be reduced to the linear support vector machine. A similar reduction was previously proven for the LASSO in 2014. The authors showed that for every instance of the elastic net, an artificial binary classification problem can be constructed such that the hyper-plane solution of a linear support vector machine (SVM) is identical to the solution β {\displaystyle \beta } (after re-scaling). The reduction immediately enables the use of highly optimized SVM solvers for elastic net problems. It also enables the use of GPU acceleration, which is often already used for large-scale SVM solvers. The reduction is a simple transformation of the original data and regularization constants X ∈ R n × p , y ∈ R n , λ 1 ≥ 0 , λ 2 ≥ 0 {\displaystyle X\in {\mathbb {R} }^{n\times p},y\in {\mathbb {R} }^{n},\lambda _{1}\geq 0,\lambda _{2}\geq 0} into new artificial data instances and a regularization constant that specify a binary classification problem and the SVM regularization constant X 2 ∈ R 2 p × n , y 2 ∈ { − 1 , 1 } 2 p , C ≥ 0. {\displaystyle X_{2}\in {\mathbb {R} }^{2p\times n},y_{2}\in \{-1,1\}^{2p},C\geq 0.} Here, y 2 {\displaystyle y_{2}} consists of binary labels − 1 , 1 {\displaystyle {-1,1}} . When 2 p > n {\displaystyle 2p>n} it is typically faster to solve the linear SVM in the primal, whereas otherwise the dual formulation is faster. Some authors have referred to the transformation as Support Vector Elastic Net (SVEN), and provided the following MATLAB pseudo-code: == Software == "Glmnet: Lasso and elastic-net regularized generalized linear models" is a software which is implemented as an R source package and as a MATLAB toolbox. This includes fast algorithms for estimation of generalized linear models with ℓ1 (the lasso), ℓ2 (ridge regression) and mixtures of the two penalties (the elastic net) using cyclical coordinate descent, computed along a regularization path. JMP Pro 11 includes elastic net regularization, using the Generalized Regression personality with Fit Model. "pensim: Simulation of high-dimensional data and parallelized repeated penalized regression" implements an alternate, parallelised "2D" tuning method of the ℓ parameters, a method claimed to result in improved prediction accuracy. scikit-learn includes linear regression and logistic regression with elastic net regularization. SVEN, a Matlab implementation of Support Vector Elastic Net. This solver reduces the Elastic Net problem to an instance of SVM binary classification and uses a Matlab SVM solver to find the solution. Because SVM is easily parallelizable, the code can be faster than Glmnet on modern hardware. SpaSM, a Matlab implementation of sparse regression, classification and principal component analysis, including elastic net regularized regression. Apache Spark provides support for Elastic Net Regression in its MLlib machine learning library. The method is available as a parameter of the more general LinearRegression class. SAS (software) The SAS procedure Glmselect and SAS Viya procedure Regselect support the use of elastic net regularization for model selection.

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  • Relation network

    Relation network

    A relation network (RN) is an artificial neural network component with a structure that can reason about relations among objects. An example category of such relations is spatial relations (above, below, left, right, in front of, behind). RNs can infer relations, they are data efficient, and they operate on a set of objects without regard to the objects' order. == History == In June 2017, DeepMind announced the first relation network. It claimed that the technology had achieved "superhuman" performance on multiple question-answering problem sets. == Design == RNs constrain the functional form of a neural network to capture the common properties of relational reasoning. These properties are explicitly added to the system, rather than established by learning just as the capacity to reason about spatial, translation-invariant properties is explicitly part of convolutional neural networks (CNN). The data to be considered can be presented as a simple list or as a directed graph whose nodes are objects and whose edges are the pairs of objects whose relationships are to be considered. The RN is a composite function: R N ( O ) = f ϕ ( ∑ i , j g θ ( o i , o j , q ) ) , {\displaystyle RN\left(O\right)=f_{\phi }\left(\sum _{i,j}g_{\theta }\left(o_{i},o_{j},q\right)\right),} where the input is a set of "objects" O = { o 1 , o 2 , . . . , o n } , o i ∈ R m {\displaystyle O=\left\lbrace o_{1},o_{2},...,o_{n}\right\rbrace ,o_{i}\in \mathbb {R} ^{m}} is the ith object, and fφ and gθ are functions with parameters φ and θ, respectively and q is the question. fφ and gθ are multilayer perceptrons, while the 2 parameters are learnable synaptic weights. RNs are differentiable. The output of gθ is a "relation"; therefore, the role of gθ is to infer any ways in which two objects are related. Image (128x128 pixel) processing is done with a 4-layer CNN. Outputs from the CNN are treated as the objects for relation analysis, without regard for what those "objects" explicitly represent. Questions were processed with a long short-term memory network.

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  • Label noise

    Label noise

    Label noise refers to errors or inaccuracies in the class labels of data instances. This is a widespread issue in machine learning datasets, arising from human annotator mistakes, unclear labeling instructions, automated labeling methods, or adversarial attacks in supervised learning. Label noise can be roughly divided into random noise, where labels are flipped independently of input features, and systematic noise, where mislabeling is dependent on certain patterns or biases in the data. Label noise can be damaging to model performance, especially for complex models that may overfit to noisy labels rather than generalizable patterns. Many approaches have been proposed to deal with the effects of label noise, including robust loss functions, noise-tolerant algorithms, data cleaning methods, and semi-supervised learning approaches. To reduce the impact of wrong labels during training, techniques like label smoothing, sample reweighting and using trusted validation sets are used. The role of noise-robust training paradigms and curriculum learning strategies to improve resilience against mislabeled data is also explored in recent research.

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  • Scale-invariant feature operator

    Scale-invariant feature operator

    In the fields of computer vision and image analysis, the scale-invariant feature operator (or SFOP) is an algorithm to detect local features in images. The algorithm was published by Förstner et al. in 2009. == Algorithm == The scale-invariant feature operator (SFOP) is based on two theoretical concepts: spiral model feature operator Desired properties of keypoint detectors: Invariance and repeatability for object recognition Accuracy to support camera calibration Interpretability: Especially corners and circles, should be part of the detected keypoints (see figure). As few control parameters as possible with clear semantics Complementarity to known detectors scale-invariant corner/circle detector. == Theory == === Maximize the weight === Maximize the weight w {\displaystyle w} = 1/variance of a point p {\displaystyle p} w ( p , α , τ , σ ) = ( N ( σ ) − 2 ) λ m i n ( M ( p , α , τ , σ ) ) Ω ( p , α , τ , σ ) {\displaystyle w(\mathbf {p} ,\alpha ,\tau ,\sigma )=\left(N(\sigma )-2\right){\frac {\lambda _{min}(M(\mathbf {p} ,\alpha ,\tau ,\sigma ))}{\Omega (\mathbf {p} ,\alpha ,\tau ,\sigma )}}} comprising: 1. the image model Ω ( p , α , τ , σ ) = ∑ n = 1 N ( σ ) [ ( q n − p ) T R α ∇ T g ( q n ) ] 2 G σ ( q n − p ) = N ( σ ) t r { R α ∇ τ ∇ τ T R α T ∗ p p T G σ ( p ) } {\displaystyle {\begin{aligned}\Omega (\mathbf {p} ,\alpha ,\tau ,\sigma )&=\sum _{n=1}^{N(\sigma )}[(\mathbf {q} _{n}-\mathbf {p} )^{T}\mathbf {R} _{\alpha }\mathbf {\nabla } _{T}g(\mathbf {q} _{n})]^{2}G_{\sigma }(\mathbf {q} _{n}-\mathbf {p} )\\&=N(\sigma )\mathbf {tr} \left\{R_{\alpha }\mathbf {\nabla } _{\tau }\mathbf {\nabla } _{\tau }^{T}R_{\alpha }^{T}\mathbf {p} \mathbf {p} ^{T}G_{\sigma }(\mathbf {p} )\right\}\end{aligned}}} 2. the smaller eigenvalue of the structure tensor M ( p , α , τ , σ ) ⏟ structure tensor = G σ ( p ) ⏟ weighted summation ∗ ( R σ ∇ τ ∇ τ T R σ T ) ⏟ squared rotated gradients {\displaystyle \underbrace {M(\mathbf {p} ,\alpha ,\tau ,\sigma )} _{\text{structure tensor}}=\underbrace {G_{\sigma }(\mathbf {p} )} _{\text{weighted summation}}\underbrace {(R_{\sigma }\nabla _{\tau }\nabla _{\tau }^{T}R_{\sigma }^{T})} _{\text{squared rotated gradients}}} === Reduce the search space === Reduce the 5-dimensional search space by linking the differentiation scale τ {\displaystyle \tau } to the integration scale τ = σ / 3 {\displaystyle \tau =\sigma /3} solving for the optimal α ^ {\displaystyle {\hat {\alpha }}} using the model Ω ( α ) = a − b cos ⁡ ( 2 α − 2 α 0 ) {\displaystyle \Omega (\alpha )=a-b\cos(2\alpha -2\alpha _{0})} and determining the parameters from three angles, e. g. Ω ( 0 ∘ ) , Ω ( 60 ∘ ) , Ω ( 120 ∘ ) → a , b , α 0 → α ^ {\displaystyle \Omega (0^{\circ }),\Omega (60^{\circ }),\Omega (120^{\circ })\quad \rightarrow \quad a,b,\alpha _{0}\quad \rightarrow \quad {\hat {\alpha }}} pre-selection possible: α = 0 ∘ → junctions , α = 90 ∘ → circular features {\displaystyle \alpha =0^{\circ }\,\rightarrow \,{\mbox{junctions}},\quad \alpha =90^{\circ }\,\rightarrow \,{\mbox{circular features}}} === Filter potential keypoints === non-maxima suppression over scale, space and angle thresholding the isotropy λ 2 ( M ) {\displaystyle \lambda _{2(M)}} :eigenvalues characterize the shape of the keypoint, smallest eigenvalue has to be larger than threshold T λ {\displaystyle T_{\lambda }} derived from noise variance V ( n ) {\displaystyle V(n)} and significance level S {\displaystyle S} : T λ ( V ( n ) , τ , σ , S ) = N ( σ ) 16 π τ 4 V ( n ) χ 2 , S 2 {\displaystyle T_{\lambda }(V(n),\tau ,\sigma ,S)={\frac {N(\sigma )}{16\pi \tau ^{4}}}V(n)\chi _{2,S}^{2}} == Algorithm == == Results == === Interpretability of SFOP keypoints ===

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  • Generalized multidimensional scaling

    Generalized multidimensional scaling

    Generalized multidimensional scaling (GMDS) is an extension of metric multidimensional scaling, in which the target space is non-Euclidean. When the dissimilarities are distances on a surface and the target space is another surface, GMDS allows finding the minimum-distortion embedding of one surface into another. GMDS is an emerging research direction. Currently, main applications are recognition of deformable objects (e.g. for three-dimensional face recognition) and texture mapping.

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  • List of datasets for machine-learning research

    List of datasets for machine-learning research

    These datasets are used in machine learning (ML) research and have been cited in peer-reviewed academic journals. Datasets are an integral part of the field of machine learning. Major advances in this field can result from advances in learning algorithms (such as deep learning), computer hardware, and, less intuitively, the availability of high-quality training datasets. High-quality labeled training datasets for supervised and semi-supervised machine-learning algorithms are usually difficult and expensive to produce because of the large amount of time needed to label the data. Although they do not need to be labeled, high-quality unlabeled datasets for unsupervised learning can also be difficult and costly to produce. Many organizations, including governments, publish and share their datasets, often using common metadata formats (such as Croissant). The datasets are classified, based on the licenses, into two groups: open data and non-open data. The datasets from various governmental-bodies are presented in List of open government data sites. The datasets are ported on open data portals. They are made available for searching, depositing and accessing through interfaces like Open API. The datasets are made available as various sorted types and subtypes. == List of sorting used for datasets == The data portal is classified based on its type of license. The open source license based data portals are known as open data portals which are used by many government organizations and academic institutions. == List of open data portals == == List of portals suitable for multiple types of applications == The data portal sometimes lists a wide variety of subtypes of datasets pertaining to many machine learning applications. == List of portals suitable for a specific subtype of applications == The data portals which are suitable for a specific subtype of machine learning application are listed in the subsequent sections. == Image data == == Text data == These datasets consist primarily of text for tasks such as natural language processing, sentiment analysis, translation, and cluster analysis. === Reviews === === News articles === === Messages === === Twitter and tweets === === Dialogues === === Legal === === Other text === == Sound data == These datasets consist of sounds and sound features used for tasks such as speech recognition and speech synthesis. === Speech === === Music === === Other sounds === == Signal data == Datasets containing electric signal information requiring some sort of signal processing for further analysis. === Electrical === === Motion-tracking === === Other signals === == Chemical data == Datasets from physical systems. === Chemical Reactions with transition states (TS) === === OpenReACT-CHON-EFH === OpenReACT-CHON-EFH (Open Reaction Dataset of Atomic ConfiguraTions comprising C, H, O and N with Energies, Forces and Hessians) is a 2025 open-access benchmark for machine-learning interatomic potentials. RTP set – 35,087 stationary-point geometries (reactant, transition state and product) drawn from 11,961 elementary reactions, each labeled with density-functional energies, atomic forces and full Hessian matrices at the ωB97X-D/6-31G(d) level. IRC set – 34,248 structures along 600 minimum-energy reaction paths, used to test extrapolation beyond trained stationary points. NMS set – 62,527 off-equilibrium geometries generated by normal-mode sampling to probe model robustness under thermal perturbations. The collection underpins the study Does Hessian Data Improve the Performance of Machine Learning Potentials? and was used to train and benchmark the machine-learning interatomic potentials reported therein. The dataset itself is distributed under a CC licence via Figshare. == Physical data == Datasets from physical systems. === High-energy physics === === Systems === === Astronomy === === Earth science === === Other physical === == Biological data == Datasets from biological systems. === Human === === Animal === === Fungi === === Plant === === Microbe === === Drug discovery === == Anomaly data == == Question answering data == This section includes datasets that deals with structured data. == Dialog or instruction prompted data == This section includes datasets that contains multi-turn text with at least two actors, a "user" and an "agent". The user makes requests for the agent, which performs the request. == Cybersecurity == == Climate and sustainability == == Code data == == Multivariate data == === Financial === === Weather === === Census === === Transit === === Internet === === Games === === Other multivariate === == Curated repositories of datasets == As datasets come in myriad formats and can sometimes be difficult to use, there has been considerable work put into curating and standardizing the format of datasets to make them easier to use for machine learning research. OpenML: Web platform with Python, R, Java, and other APIs for downloading hundreds of machine learning datasets, evaluating algorithms on datasets, and benchmarking algorithm performance against dozens of other algorithms. PMLB: A large, curated repository of benchmark datasets for evaluating supervised machine learning algorithms. Provides classification and regression datasets in a standardized format that are accessible through a Python API. Metatext NLP: https://metatext.io/datasets web repository maintained by community, containing nearly 1000 benchmark datasets, and counting. Provides many tasks from classification to QA, and various languages from English, Portuguese to Arabic. Appen: Off The Shelf and Open Source Datasets hosted and maintained by the company. These biological, image, physical, question answering, signal, sound, text, and video resources number over 250 and can be applied to over 25 different use cases.

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  • Trigger list

    Trigger list

    Trigger list in its most general meaning refers to a list whose items are used to initiate ("trigger") certain actions. == United States: Private financial information == In the United States, when a person applies for a mortgage loan, the lender makes a credit inquiry about the potential borrower from the national credit bureaus, Equifax, Experian and TransUnion. Unless the borrower is opted out, the credit bureaus put the applicants onto a "trigger list" of "leads" about persons who are interested in new loans. These lists are sold to numerous lenders all over the United States, and soon after the application the applicant starts receiving offers from all parts of the country. The trigger lists contain a significant amount of personal financial information. Among the buyers of trigger lists are "lead generators" which resell filtered information to borrowers, e.g., of people who live in a certain area and have a certain credit score. While the Federal Trade Commission considers the market of "trigger lists" to be a legal business, many people and organizations (such as the National Association of Mortgage Brokers) consider this a serious breach of privacy and lobby for putting this practice under regulatory controls. As of now, American consumers may opt-out from "trigger lists" by calling 1-888-5-OPTOUT (1-888-567-8688). == Nuclear non-proliferation == The Zangger Committee and the Nuclear Suppliers Group maintain lists of items that may contribute to nuclear proliferation; The nuclear non-proliferation treaty forbids its members to export such items to non-treaty members. these items are said to trigger the countries' responsibilities under the NPT, hence the name.

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  • Operational taxonomic unit

    Operational taxonomic unit

    An operational taxonomic unit (OTU) is an operational definition used to classify groups of closely related individuals. The term was originally introduced in 1963 by Robert R. Sokal and Peter H. A. Sneath in the context of numerical taxonomy, where an "operational taxonomic unit" is simply the group of organisms currently being studied. In this sense, an OTU is a pragmatic definition to group individuals by similarity, equivalent to but not necessarily in line with classical Linnaean taxonomy or modern evolutionary taxonomy. Nowadays, however, the term is commonly used in a different context and refers to clusters of (uncultivated or unknown) organisms, grouped by DNA sequence similarity of a specific taxonomic marker gene (originally coined as mOTU; molecular OTU). In other words, OTUs are pragmatic proxies for "species" at different taxonomic levels, in the absence of traditional systems of biological classification as are available for macroscopic organisms. For several years, OTUs have been the most commonly used units of diversity, especially when analysing small subunit 16S (for prokaryotes) or 18S rRNA (for eukaryotes) marker gene sequence datasets. == Molecular OTU by clustering of marker gene sequences == In the approach represented by DNA barcoding, a particular locus is chosen to be used as the marker gene for classification. This locus should be universally present in the scope selected, variable enough to be different among close-related species, and be flanked by conservative sequences that allow for easy amplification and detection. There are databases containing sequences for such marker genes from many different species, allowing for comparison. (Sometimes only using one locus does not provide sufficient resolution, so multiple marker genes are used. This is the case for plants, where rbcL+matK is common.) Sequences obtained this way can be clustered according to their similarity to one another, and operational taxonomic units are defined based on the similarity threshold set by the researcher. The exact threshold depends on the taxa in question and the mutational rates of the selected locus in the taxon. 97–99% are commonly used, but "it is now recognized to be somewhat arbitrary as sequence variation within and among species varies across taxa". 100% similarity (fully identical) is also common, also known as single variants. It remains debatable how well this commonly used method recapitulates true microbial species phylogeny or ecology. Although OTUs can be calculated differently when using different algorithms or thresholds, research by Schmidt et al. (2014) demonstrated that 16S-derived microbial OTUs were generally ecologically consistent across habitats and several clustering approaches. The number of OTUs defined may be inflated due to errors in DNA sequencing. === OTU clustering approaches === There are three main approaches to clustering OTUs: De novo, for which the clustering is based on similarities between sequencing reads. Closed-reference, for which the clustering is performed against a reference database of sequences. Open-reference, where clustering is first performed against a reference database of sequences, then any remaining sequences that could not be mapped to the reference are clustered de novo. Using a reference provides taxonomic context for the OTUs found. Alternatively, taxonomic context can be found after the construction of clusters by comparing representative sequences from clusters against a reference database. There are also specialized classifiers for this purpose which are much faster than naive comparison using BLAST. === OTU clustering algorithms === Hierarchical clustering algorithms (HCA): uclust & cd-hit & ESPRIT Bayesian clustering: CROP == Molecular OTU by other methods == In addition to similarity-based grouping, marker gene sequences can be sorted into OTUs using molecular phylogeny, k-mer composition, or hybrid methods combining these methods with similarity. There are also Bayesian tree-less methods and machine learning approaches. Using phylogeny often involves manually assigning terminal clades or single nodes to an OTU, so this is usually only done for refinement. Genome skimming can be used to obtain high-copy DNA without the need to choose marker genes or to design PCR primers for the chosen genes. It can provide fairly good coverage of organelle DNA and repetitive elements such as ribosomal DNA, both of which can be used like marker genes in OTU analysis. Whole-genome sequencing is more expensive and involves the production and processing of more data. By considering the entire genome, many (sometimes over 100) marker genes can be used at the same time, producing highly resolved phylogenies that correctly identify problematic taxa. It is also possible to use entire genomes for OTU assignment. For example, genomes from different bacterial species almost always have an average nucleotide identity lower than 95%, a fact that can be used to define new OTUs (and likely new species).

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  • Tanagra (machine learning)

    Tanagra (machine learning)

    Tanagra is a free suite of machine learning software for research and academic purposes developed by Ricco Rakotomalala at the Lumière University Lyon 2, France. Tanagra supports several standard data mining tasks such as: Visualization, Descriptive statistics, Instance selection, feature selection, feature construction, regression, factor analysis, clustering, classification and association rule learning. Tanagra is an academic project. It is widely used in French-speaking universities. Tanagra is frequently used in real studies and in software comparison papers. == History == The development of Tanagra was started in June 2003. The first version was distributed in December 2003. Tanagra is the successor of Sipina, another free data mining tool which is intended only for supervised learning tasks (classification), especially the interactive and visual construction of decision trees. Sipina is still available online and is maintained. Tanagra is an "open source project" as every researcher can access the source code and add their own algorithms, as long as they agree and conform to the software distribution license. The main purpose of the Tanagra project is to give researchers and students a user-friendly data mining software, conforming to the present norms of the software development in this domain (especially in the design of its GUI and the way to use it), and allowing the analyzation of either real or synthetic data. From 2006, Ricco Rakotomalala made an important documentation effort. A large number of tutorials are published on a dedicated website. They describe the statistical and machine learning methods and their implementation with Tanagra on real case studies. The use of other free data mining tools on the same problems is also widely described. The comparison of the tools enables readers to understand the possible differences in the presentation of results. == Description == Tanagra works similarly to current data mining tools. The user can design visually a data mining process in a diagram. Each node is a statistical or machine learning technique, the connection between two nodes represents the data transfer. But unlike the majority of tools which are based on the workflow paradigm, Tanagra is very simplified. The treatments are represented in a tree diagram. The results are displayed in an HTML format. This makes it is easy to export the outputs in order to visualize the results in a browser. It is also possible to copy the result tables to a spreadsheet. Tanagra makes a good compromise between statistical approaches (e.g. parametric and nonparametric statistical tests), multivariate analysis methods (e.g. factor analysis, correspondence analysis, cluster analysis, regression) and machine learning techniques (e.g. neural network, support vector machine, decision trees, random forest).

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  • Radial basis function

    Radial basis function

    In mathematics a radial basis function (RBF) is a real-valued function φ {\textstyle \varphi } whose value depends only on the distance between the input and some fixed point, either the origin, so that φ ( x ) = φ ^ ( ‖ x ‖ ) {\textstyle \varphi (\mathbf {x} )={\hat {\varphi }}(\left\|\mathbf {x} \right\|)} , or some other fixed point c {\textstyle \mathbf {c} } , called a center, so that φ ( x ) = φ ^ ( ‖ x − c ‖ ) {\textstyle \varphi (\mathbf {x} )={\hat {\varphi }}(\left\|\mathbf {x} -\mathbf {c} \right\|)} . Any function φ {\textstyle \varphi } that satisfies the property φ ( x ) = φ ^ ( ‖ x ‖ ) {\textstyle \varphi (\mathbf {x} )={\hat {\varphi }}(\left\|\mathbf {x} \right\|)} is a radial function. The distance is usually Euclidean distance, although other metrics are sometimes used. They are often used as a collection { φ k } k {\displaystyle \{\varphi _{k}\}_{k}} which forms a basis for some function space of interest, hence the name. Sums of radial basis functions are typically used to approximate given functions. This approximation process can also be interpreted as a simple kind of neural network; this was the context in which they were originally applied to machine learning, in work by David Broomhead and David Lowe in 1988, which stemmed from Michael J. D. Powell's seminal research from 1977. RBFs are also used as a kernel in support vector classification. The technique has proven effective and flexible enough that radial basis functions are now applied in a variety of engineering applications. == Definition == A radial function is a function φ : [ 0 , ∞ ) → R {\textstyle \varphi :[0,\infty )\to \mathbb {R} } . When paired with a norm ‖ ⋅ ‖ : V → [ 0 , ∞ ) {\textstyle \|\cdot \|:V\to [0,\infty )} on a vector space, a function of the form φ c = φ ( ‖ x − c ‖ ) {\textstyle \varphi _{\mathbf {c} }=\varphi (\|\mathbf {x} -\mathbf {c} \|)} is said to be a radial kernel centered at c ∈ V {\textstyle \mathbf {c} \in V} . A radial function and the associated radial kernels are said to be radial basis functions if, for any finite set of nodes { x k } k = 1 n ⊆ V {\displaystyle \{\mathbf {x} _{k}\}_{k=1}^{n}\subseteq V} , all of the following conditions are true: === Examples === Commonly used types of radial basis functions include (writing r = ‖ x − x i ‖ {\textstyle r=\left\|\mathbf {x} -\mathbf {x} _{i}\right\|} and using ε {\textstyle \varepsilon } to indicate a shape parameter that can be used to scale the input of the radial kernel): == Approximation == Radial basis functions are typically used to build up function approximations of the form where the approximating function y ( x ) {\textstyle y(\mathbf {x} )} is represented as a sum of N {\displaystyle N} radial basis functions, each associated with a different center x i {\textstyle \mathbf {x} _{i}} , and weighted by an appropriate coefficient w i . {\textstyle w_{i}.} The weights w i {\textstyle w_{i}} can be estimated using the matrix methods of linear least squares, because the approximating function is linear in the weights w i {\textstyle w_{i}} . Approximation schemes of this kind have been particularly used in time series prediction and control of nonlinear systems exhibiting sufficiently simple chaotic behaviour and 3D reconstruction in computer graphics (for example, hierarchical RBF and Pose Space Deformation). == RBF Network == The sum can also be interpreted as a rather simple single-layer type of artificial neural network called a radial basis function network, with the radial basis functions taking on the role of the activation functions of the network. It can be shown that any continuous function on a compact interval can in principle be interpolated with arbitrary accuracy by a sum of this form, if a sufficiently large number N {\textstyle N} of radial basis functions is used. The approximant y ( x ) {\textstyle y(\mathbf {x} )} is differentiable with respect to the weights w i {\textstyle w_{i}} . The weights could thus be learned using any of the standard iterative methods for neural networks. Using radial basis functions in this manner yields a reasonable interpolation approach provided that the fitting set has been chosen such that it covers the entire range systematically (equidistant data points are ideal). However, without a polynomial term that is orthogonal to the radial basis functions, estimates outside the fitting set tend to perform poorly. == RBFs for PDEs == Radial basis functions are used to approximate functions and so can be used to discretize and numerically solve Partial Differential Equations (PDEs). This was first done in 1990 by E. J. Kansa who developed the first RBF based numerical method. It is called the Kansa method and was used to solve the elliptic Poisson equation and the linear advection-diffusion equation. The function values at points x {\displaystyle \mathbf {x} } in the domain are approximated by the linear combination of RBFs: The derivatives are approximated as such: where N {\displaystyle N} are the number of points in the discretized domain, d {\displaystyle d} the dimension of the domain and λ {\displaystyle \lambda } the scalar coefficients that are unchanged by the differential operator. Different numerical methods based on Radial Basis Functions were developed thereafter. Some methods are the RBF-FD method, the RBF-QR method and the RBF-PUM method.

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  • Discrete skeleton evolution

    Discrete skeleton evolution

    Discrete Skeleton Evolution (DSE) describes an iterative approach to reducing a morphological or topological skeleton. It is a form of pruning in that it removes noisy or redundant branches (spurs) generated by the skeletonization process, while preserving information-rich "trunk" segments. The value assigned to individual branches varies from algorithm to algorithm, with the general goal being to convey the features of interest of the original contour with a few carefully chosen lines. Usually, clarity for human vision (aka. the ability to "read" some features of the original shape from the skeleton) is valued as well. DSE algorithms are distinguished by complex, recursive decision-making processes with high computational requirements. Pruning methods such as by structuring element (SE) convolution and the Hough transform are general purpose algorithms which quickly pass through an image and eliminate all branches shorter than a given threshold. DSE methods are most applicable when detail retention and contour reconstruction are valued. == Methodology == === Pre-processing === Input images will typical contain more data than is necessary to generate an initial skeleton, and thus must be reduced in some way. Reducing the resolution, converting to grayscale, and then binary by masking or thresholding are common first steps. Noise removal may occur before and/or after converting an image to binary. Morphological operations such as closing, opening, and smoothing of the binary image may also be part of pre-processing. Ideally, the binarized contour should be as noise-free as possible before the skeleton is generated. === Skeletonization === DSE techniques may be applied to an existing skeleton or incorporated as part of the skeleton growing algorithm. Suitable skeletons may be obtained using a variety of methods: Thinning algorithms, such as the Grassfire transform Voronoi diagram Medial Axis Transform or Symmetry Axis Transform Distance Mapping === Significance Measures === DSE and related methods remove entire spurious branches while leaving the main trunk intact. The intended result is typically optimized for visual clarity and retention of information, such that the original contour can be reconstructed from the fully pruned skeleton. The value of various properties must be weighted by the application, and improving the efficiency is an ongoing topic of research in computer vision and image processing. Some significance measures include: Discrete Bisector Function Contour length Bending Potential Ratio Discrete Curve Evolution === Iteration === Each branch is evaluated during a pass through the skeletonized image according to the specific algorithm being used. Low value branches are removed and the process is repeated until a desired threshold of simplicity is reached. === Reconstruction === If all points on the output skeleton are the center points of maximal disks of the image and the radius information is retained, a contour image can be reconstructed == Applications == === Handwriting and text parsing === Variability in hand-written text is an ongoing challenge, simplification makes it somewhat easier for computer vision algorithms to make judgements about intended characters. === Soft body classification (animals) === The maximal disks centered on the skeleton imply roughly spherical masses, the features of the extracted skeleton are relatively unchanged even as the soft body deforms or self-occludes. Skeleton information is one facet of determining whether two animals are the "same" some way, though it must usually be paired with another technique to effectively identify a target. === Medical uses === Investigation of organs, tissue damage and deformation caused by disease.

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  • Taguchi loss function

    Taguchi loss function

    The Taguchi loss function is graphical depiction of loss developed by the Japanese business statistician Genichi Taguchi to describe a phenomenon affecting the value of products produced by a company. Praised by Dr. W. Edwards Deming (the business guru of the 1980s American quality movement), it made clear the concept that quality does not suddenly plummet when, for instance, a machinist exceeds a rigid blueprint tolerance. Instead 'loss' in value progressively increases as variation increases from the intended condition. This was considered a breakthrough in describing quality, and helped fuel the continuous improvement movement. The concept of Taguchi's quality loss function was in contrast with the American concept of quality, popularly known as goal post philosophy, the concept given by American quality guru Phil Crosby. Goal post philosophy emphasizes that if a product feature doesn't meet the designed specifications it is termed as a product of poor quality (rejected), irrespective of amount of deviation from the target value (mean value of tolerance zone). This concept has similarity with the concept of scoring a 'goal' in the game of football or hockey, because a goal is counted 'one' irrespective of the location of strike of the ball in the 'goal post', whether it is in the center or towards the corner. This means that if the product dimension goes out of the tolerance limit the quality of the product drops suddenly. Through his concept of the quality loss function, Taguchi explained that from the customer's point of view this drop of quality is not sudden. The customer experiences a loss of quality the moment product specification deviates from the 'target value'. This 'loss' is depicted by a quality loss function and it follows a parabolic curve mathematically given by L = k(y–m)2, where m is the theoretical 'target value' or 'mean value' and y is the actual size of the product, k is a constant and L is the loss. This means that if the difference between 'actual size' and 'target value' i.e. (y–m) is large, loss would be more, irrespective of tolerance specifications. In Taguchi's view tolerance specifications are given by engineers and not by customers; what the customer experiences is 'loss'. This equation is true for a single product; if 'loss' is to be calculated for multiple products the loss function is given by L = k[S2 + ( y ¯ {\displaystyle {\bar {y}}} – m)2], where S2 is the 'variance of product size' and y ¯ {\displaystyle {\bar {y}}} is the average product size. == Overview == The Taguchi loss function is important for a number of reasons—primarily, to help engineers better understand the importance of designing for variation.

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  • Radial basis function network

    Radial basis function network

    In the field of mathematical modeling, a radial basis function network is an artificial neural network that uses radial basis functions as activation functions. The output of the network is a linear combination of radial basis functions of the inputs and neuron parameters. Radial basis function networks have many uses, including function approximation, time series prediction, classification, and system control. They were first formulated in a 1988 paper by Broomhead and Lowe, both researchers at the Royal Signals and Radar Establishment. == Network architecture == Radial basis function (RBF) networks typically have three layers: an input layer, a hidden layer with a non-linear RBF activation function and a linear output layer. The input can be modeled as a vector of real numbers x ∈ R n {\displaystyle \mathbf {x} \in \mathbb {R} ^{n}} . The output of the network is then a scalar function of the input vector, φ : R n → R {\displaystyle \varphi :\mathbb {R} ^{n}\to \mathbb {R} } , and is given by φ ( x ) = ∑ i = 1 N a i ρ ( | | x − c i | | ) {\displaystyle \varphi (\mathbf {x} )=\sum _{i=1}^{N}a_{i}\rho (||\mathbf {x} -\mathbf {c} _{i}||)} where N {\displaystyle N} is the number of neurons in the hidden layer, c i {\displaystyle \mathbf {c} _{i}} is the center vector for neuron i {\displaystyle i} , and a i {\displaystyle a_{i}} is the weight of neuron i {\displaystyle i} in the linear output neuron. Functions that depend only on the distance from a center vector are radially symmetric about that vector, hence the name radial basis function. In the basic form, all inputs are connected to each hidden neuron. The norm is typically taken to be the Euclidean distance (although the Mahalanobis distance appears to perform better with pattern recognition) and the radial basis function is commonly taken to be Gaussian ρ ( ‖ x − c i ‖ ) = exp ⁡ [ − β i ‖ x − c i ‖ 2 ] {\displaystyle \rho {\big (}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert {\big )}=\exp \left[-\beta _{i}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert ^{2}\right]} . The Gaussian basis functions are local to the center vector in the sense that lim | | x | | → ∞ ρ ( ‖ x − c i ‖ ) = 0 {\displaystyle \lim _{||x||\to \infty }\rho (\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert )=0} i.e. changing parameters of one neuron has only a small effect for input values that are far away from the center of that neuron. Given certain mild conditions on the shape of the activation function, RBF networks are universal approximators on a compact subset of R n {\displaystyle \mathbb {R} ^{n}} . This means that an RBF network with enough hidden neurons can approximate any continuous function on a closed, bounded set with arbitrary precision. The parameters a i {\displaystyle a_{i}} , c i {\displaystyle \mathbf {c} _{i}} , and β i {\displaystyle \beta _{i}} are determined in a manner that optimizes the fit between φ {\displaystyle \varphi } and the data. === Normalization === ==== Normalized architecture ==== In addition to the above unnormalized architecture, RBF networks can be normalized. In this case the mapping is φ ( x ) = d e f ∑ i = 1 N a i ρ ( ‖ x − c i ‖ ) ∑ i = 1 N ρ ( ‖ x − c i ‖ ) = ∑ i = 1 N a i u ( ‖ x − c i ‖ ) {\displaystyle \varphi (\mathbf {x} )\ {\stackrel {\mathrm {def} }{=}}\ {\frac {\sum _{i=1}^{N}a_{i}\rho {\big (}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert {\big )}}{\sum _{i=1}^{N}\rho {\big (}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert {\big )}}}=\sum _{i=1}^{N}a_{i}u{\big (}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert {\big )}} where u ( ‖ x − c i ‖ ) = d e f ρ ( ‖ x − c i ‖ ) ∑ j = 1 N ρ ( ‖ x − c j ‖ ) {\displaystyle u{\big (}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert {\big )}\ {\stackrel {\mathrm {def} }{=}}\ {\frac {\rho {\big (}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert {\big )}}{\sum _{j=1}^{N}\rho {\big (}\left\Vert \mathbf {x} -\mathbf {c} _{j}\right\Vert {\big )}}}} is known as a normalized radial basis function. ==== Theoretical motivation for normalization ==== There is theoretical justification for this architecture in the case of stochastic data flow. Assume a stochastic kernel approximation for the joint probability density P ( x ∧ y ) = 1 N ∑ i = 1 N ρ ( ‖ x − c i ‖ ) σ ( | y − e i | ) {\displaystyle P\left(\mathbf {x} \land y\right)={1 \over N}\sum _{i=1}^{N}\,\rho {\big (}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert {\big )}\,\sigma {\big (}\left\vert y-e_{i}\right\vert {\big )}} where the weights c i {\displaystyle \mathbf {c} _{i}} and e i {\displaystyle e_{i}} are exemplars from the data and we require the kernels to be normalized ∫ ρ ( ‖ x − c i ‖ ) d n x = 1 {\displaystyle \int \rho {\big (}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert {\big )}\,d^{n}\mathbf {x} =1} and ∫ σ ( | y − e i | ) d y = 1 {\displaystyle \int \sigma {\big (}\left\vert y-e_{i}\right\vert {\big )}\,dy=1} . The probability densities in the input and output spaces are P ( x ) = ∫ P ( x ∧ y ) d y = 1 N ∑ i = 1 N ρ ( ‖ x − c i ‖ ) {\displaystyle P\left(\mathbf {x} \right)=\int P\left(\mathbf {x} \land y\right)\,dy={1 \over N}\sum _{i=1}^{N}\,\rho {\big (}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert {\big )}} and The expectation of y given an input x {\displaystyle \mathbf {x} } is φ ( x ) = d e f E ( y ∣ x ) = ∫ y P ( y ∣ x ) d y {\displaystyle \varphi \left(\mathbf {x} \right)\ {\stackrel {\mathrm {def} }{=}}\ E\left(y\mid \mathbf {x} \right)=\int y\,P\left(y\mid \mathbf {x} \right)dy} where P ( y ∣ x ) {\displaystyle P\left(y\mid \mathbf {x} \right)} is the conditional probability of y given x {\displaystyle \mathbf {x} } . The conditional probability is related to the joint probability through Bayes' theorem P ( y ∣ x ) = P ( x ∧ y ) P ( x ) {\displaystyle P\left(y\mid \mathbf {x} \right)={\frac {P\left(\mathbf {x} \land y\right)}{P\left(\mathbf {x} \right)}}} which yields φ ( x ) = ∫ y P ( x ∧ y ) P ( x ) d y {\displaystyle \varphi \left(\mathbf {x} \right)=\int y\,{\frac {P\left(\mathbf {x} \land y\right)}{P\left(\mathbf {x} \right)}}\,dy} . This becomes φ ( x ) = ∑ i = 1 N e i ρ ( ‖ x − c i ‖ ) ∑ i = 1 N ρ ( ‖ x − c i ‖ ) = ∑ i = 1 N e i u ( ‖ x − c i ‖ ) {\displaystyle \varphi \left(\mathbf {x} \right)={\frac {\sum _{i=1}^{N}e_{i}\rho {\big (}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert {\big )}}{\sum _{i=1}^{N}\rho {\big (}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert {\big )}}}=\sum _{i=1}^{N}e_{i}u{\big (}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert {\big )}} when the integrations are performed. === Local linear models === It is sometimes convenient to expand the architecture to include local linear models. In that case the architectures become, to first order, φ ( x ) = ∑ i = 1 N ( a i + b i ⋅ ( x − c i ) ) ρ ( ‖ x − c i ‖ ) {\displaystyle \varphi \left(\mathbf {x} \right)=\sum _{i=1}^{N}\left(a_{i}+\mathbf {b} _{i}\cdot \left(\mathbf {x} -\mathbf {c} _{i}\right)\right)\rho {\big (}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert {\big )}} and φ ( x ) = ∑ i = 1 N ( a i + b i ⋅ ( x − c i ) ) u ( ‖ x − c i ‖ ) {\displaystyle \varphi \left(\mathbf {x} \right)=\sum _{i=1}^{N}\left(a_{i}+\mathbf {b} _{i}\cdot \left(\mathbf {x} -\mathbf {c} _{i}\right)\right)u{\big (}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert {\big )}} in the unnormalized and normalized cases, respectively. Here b i {\displaystyle \mathbf {b} _{i}} are weights to be determined. Higher order linear terms are also possible. This result can be written φ ( x ) = ∑ i = 1 2 N ∑ j = 1 n e i j v i j ( x − c i ) {\displaystyle \varphi \left(\mathbf {x} \right)=\sum _{i=1}^{2N}\sum _{j=1}^{n}e_{ij}v_{ij}{\big (}\mathbf {x} -\mathbf {c} _{i}{\big )}} where e i j = { a i , if i ∈ [ 1 , N ] b i j , if i ∈ [ N + 1 , 2 N ] {\displaystyle e_{ij}={\begin{cases}a_{i},&{\mbox{if }}i\in [1,N]\\b_{ij},&{\mbox{if }}i\in [N+1,2N]\end{cases}}} and v i j ( x − c i ) = d e f { δ i j ρ ( ‖ x − c i ‖ ) , if i ∈ [ 1 , N ] ( x i j − c i j ) ρ ( ‖ x − c i ‖ ) , if i ∈ [ N + 1 , 2 N ] {\displaystyle v_{ij}{\big (}\mathbf {x} -\mathbf {c} _{i}{\big )}\ {\stackrel {\mathrm {def} }{=}}\ {\begin{cases}\delta _{ij}\rho {\big (}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert {\big )},&{\mbox{if }}i\in [1,N]\\\left(x_{ij}-c_{ij}\right)\rho {\big (}\left\Vert \mathbf {x} -\mathbf {c} _{i}\right\Vert {\big )},&{\mbox{if }}i\in [N+1,2N]\end{cases}}} in the unnormalized case and in the normalized case. Here δ i j {\displaystyle \delta _{ij}} is a Kronecker delta function defined as δ i j = { 1 , if i = j 0 , if i ≠ j {\displaystyle \delta _{ij}={\begin{cases}1,&{\mbox{if }}i=j\\0,&{\mbox{if }}i\neq j\end{cases}}} . == Training == RBF networks are typically trained from pairs of input and target values x ( t ) , y ( t ) {\displaystyle \mathbf {x} (t),y(t)} , t = 1 , … , T {\displaystyle t=1,\dots ,T} by a two-step algorithm. In the first step, the center vectors c i {\displaystyle \mathbf {c} _{i}} of the RBF functions in the hidden layer

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